MERS-CoV

MIDDLE EAST RESPIRATORY SYNDROME (MERS)

Middle East Respiratory Syndrome (MERS) is an illness cause by a virus (more specifically, a coronavirus) called Middle East Respiratory Syndrome Coronavirus (MERS-CoV). MERS affects the respiratory system (lungs and breathing tubes). Most MERS patients developed severe acute respiratory illness with symptoms of fever, cough and shortness of breath. About 30% of them died.

The source of MERS-CoV is still uncertain. However, it likely came from an animal source. In addition to humans, MERS-CoV has been found in camels in Qatar, Oman, Egypt, and Saudi Arabia, and a bat in Saudi Arabia.

MERS can affect anyone. MERS patients have ranged in age from younger than 1 to 94 years old. Based on what researchers know so far, people with pre-existing medical conditions or comorbidities, may be more likely to become infected with MERS, or have a severe case. Individuals with weakened immune systems are also at higher risk for getting MERS or hacing a severe case.

Incubation Period: 

  • 2-14 days

Signs and Symptoms:

  • Fever
  • Cough
  • Shortness of breath
  • Some with gastrointestinal symptoms (diarrhea, nausea and vomiting)

Complications:

  • Pneumonia
  • Severe Kidney failure

Transmission:

  • Close contact, such as caring for or living with an infected person.
  • All reported cases have been linked to countries in and near the Arabian Peninsula.
  • MERS-CoV remains stable as an aerosol and at low temperature on plastic/steel and can be recovered after 48 hours.
  • MERS-CoV is more stable than influenza A (H1N1) virus in both aerosol and on surfaces.

Work-Up:

  • rRT-PCR assay of respiratory, blood, and stool specimens
  • For short periods (<72 hours), most specimens should be held at 2-8°C rather than frozen. For delays exceeding 72 hours, freeze specimens at -70°C as soon as possible after collection.

Prevention & Treatment:

  • No vaccine to prevent MERS-CoV infection
  • Hand-washing with soap and water for 20 seconds. If soap and water are not available, use an alcohol-based hand sanitizer.
  • Cover nose and mouth with tissue when coughing or sneezing.
  • Avoid touching the eyes, nose, and mouth with unwashed hands.
  • Avoid personal contact, such as kissing, or sharing cups or eating utensils, with sick people.
  • Clean and disinfect frequently touched surfaces such as toys and doorknobs.
  • No specific antiviral treatment recommended for MERS-CoV infection.
  • Current treatment includes care to support vital organ functions

Countries with Lab-Confirmed MERS Cases:

  • Saudi Arabia
  • United Arab Emirates
  • Qatar
  • Oman
  • Jordan
  • Kuwait
  • Yemen
  • Lebanon
  • United Kingdom
  • France
  • Tunisia
  • Italy
  • Malaysia
  • The Philippines
  • Greece
  • Egypt
  • United States of America
  • The Netherlands

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